Step-by-step clinical titration schedules, receptor adaptation, and administration instructions.
Primary Pharmacological Mechanism: Selective dopamine transporter (DAT) inhibition in the striatum coupled with hypothalamic orexin-A and histamine receptor activation, enhancing wakefulness and executive working memory.
Clinical Protocol Summary: 100mg to 200mg once daily upon waking. 15-hour half-life provides sustained prefrontal cortex focus without the peripheral tachycardia of amphetamines.
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